Christina Walters (Cameron Diaz) and her friends Courtney (Christina Applegate) and Jane (Selma Blair) are three attractive women who share a floor addicted to fun. They also love the nightlife and enjoy their bachelorhood without looking for something serious in their relationships with men. However, one night at the city’s hot spot, Christina meets Peter (Thomas Jane). Immediately she is captivated by him and believes that it can be – finally! – of his ideal man.
Thus, the next morning Christina desperately looks for Peter, but discovers that he has already left the hotel where he was staying. She is clear that she is not willing to throw in the towel and a desperate idea occurs to her: to undertake a long and crazy road trip with the intention of finding the one who believes that it can be the great love of her life. Cameron Diaz heads the cast of this romantic comedy in which she plays her most casual role to be remembered to date.