The director of Monster High, Mrs. Good Blood, has a great plan in mind: to put vampires and werewolves together in the same institute so that they can forget their old aversion and become friends once and for all. But this idea does not go as planned and a human specialist in monsters, named Van Hellscream, is called to help the school against the open war between vampires and werewolves.
At first, Van Hellscream seems to be a good person, but although he knows the monsters he is human and does not seem to be the one to work as a school principal. Van Hellscream creates a disturbed environment. Frankie Stein and her classmates should help Director Good Blood and get Monster High students reconciled.